Tried this and worked fine as long as we don't run Adobe Updates, this fix should stay in place. Also, Gamiel confirmed how he Saved Files as PDF vs. using the plugin. Applied the same fix on Kylie's Macbook and has been working fine.

1.       Close all Office applications
2.       Go to /Library/Application Support/Microsoft/Office365/User Content.localized/Startup/

              

           3.   In the Excel folder, delete SaveAsAdobePDF.ppam.

    

          4. In the Word folder, delete LinkCreation.dotm


          5.  In the PowerPoint folder, delete SaveAsAdobePDF.ppam

 

           6.  Re-open the Office applications and confirm the issue is resolved


           If issue is not resolved move to step 7 and beyond to remove from the application.

 


Unfortunately that does not solve the problem for PowerPoint or Excel because if I remove SaveAsAdobePDF.ppam inside the PowerPoint folder or the SaveAsAdobePDF.xlam inside the Excel folder will trigger another error on application launch.
To fix these errors, you need to:

7.       Launch Excel and PowerPoint and go to the menu Tools -> Excel Add-ins... and Tools -> PowerPoint Add-ins..., respectively, and remove the Save as Adobe PDF add-in, by unchecking it and removing it with the "-" button and then click OK.
8.       Restart Excel and PowerPoint and the problem should go away. If not, try several times to remove those options from the Tools menu until the problem goes away. I had to repeat this procedure in PowerPoint until this got fixed.


FROM: https://apple.stackexchange.com/questions/407353/how-to-fix-run-time-error-53-every-time-i-open-a-document-in-word-or-a-worksheet


https://services.dartmouth.edu/TDClient/1806/Portal/KB/ArticleDet?ID=151641#:~:text=Click%20Go%20menu.,confirm%20the%20issue%20is%20resolved.


Thanks,

Audel


Updated By Kyle 10-1-24